IGF-1 LR3 1MG

$89.99

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What is IGF-1 LR3 1MG?

IGF-1 LR3 (Insulin-like Growth Factor-1 Long Arginine 3) is a recombinant analogue of human IGF-1, modified to enhance stability and bioavailability. It differs from native IGF-1 by substitution of an arginine for glutamic acid at position 3 and the addition of 13 amino acids to the N-terminus. These changes reduce binding to IGF-binding proteins, extending its half-life and enabling prolonged biological activity. IGF-1 LR3 functions as a potent growth-factor agonist, influencing cellular proliferation, differentiation, and repair in laboratory settings.
Structure of Chemicals iron peptides

Chemical Structure of IGF-1 LR3 1MG

  • Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA

  • Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉

  • Molecular Weight: ≈ 9117.5 Da

  • CAS Number: 946870-92-4
    This engineered peptide shares tertiary similarity to endogenous IGF-1 but exhibits markedly reduced affinity for serum IGF-binding proteins, resulting in a plasma persistence approximately 120 times longer than native IGF-1.

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What Are the Effects of IGF-1 LR3 1MG?

  • Cellular Proliferation: Stimulates mitogenesis and differentiation in muscle, bone, and connective tissue models; promotes cell division in hepatic, renal, neural, and epithelial systems.

  • Metabolic Regulation: Interacts with both IGF-1 and insulin receptors, enhancing glucose uptake and influencing lipid metabolism in preclinical studies.

  • Myostatin Modulation: Evidence from murine and in-vitro models suggests IGF-1 LR3 attenuates myostatin signaling, supporting muscle regeneration and protecting myoblasts from apoptosis.

  • Tissue Repair and Longevity Research: Investigated for its role in supporting tissue maintenance and repair, and in delaying cellular senescence in mammalian aging studies.

  • Glucocorticoid Interaction: Experimental data indicate potential mitigation of glucocorticoid-induced muscle wasting in research models.


Research-Use Disclaimer:

IGF-1 LR3 is supplied strictly for laboratory and research purposes only. It is not approved for human or veterinary use. All biological effects described above are derived from preclinical or in-vitro data and should not be interpreted as clinical outcomes.

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Drew Hahn

2025-09-09

I decided to try something new with…

I decided to try something new with Iron Peptides, and it has already been very beneficial. Since starting, I’ve noticed many positive effects. I feel motivated to continue, and I’m confident I’ve found the right company to trust on my personal journey—Iron Peptides.

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2025-09-07

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The products, services and information is exceptional

Karla Rodriguez

2025-09-07

Fist time trying peptides to see what…

Fist time trying peptides to see what all the hype was about. And. I AM HOOKED! Have never felt. Better. 5 months after my neck surgery and I feel amazing. Recovery was easy and I have all my strength back!!

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IGF-1 LR3 1MGIGF-1 LR3 1MG
$89.99

Availability: 19 in stock

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